相关产品推荐更多 >

HSZFP36 Rabbit Polyclonal Antibody (HRP) 抗体,orb2138407,Biorbyt
¥0
IL6ST/CD130 Rabbit Polyclonal Antibody 抗体,orb10914,Biorbyt
¥3159
MAPK3 Rabbit Polyclonal Antibody 抗体,orb2954478,Biorbyt
¥2925
KCNG1 Rabbit Polyclonal Antibody 抗体,orb157732,Biorbyt
¥3159
Urokinase Rabbit Polyclonal Antibody 抗体,orb11278,Biorbyt
¥3159
万千商家帮你免费找货
0 人在求购买到急需产品
相关阅读
阿拉丁试剂,充足现货,稳定批间差abinScience 体内级抗体,年度锁价,低至 1200五大应用案例:Mustang Q 膜层析应用全解析1 个小工具,一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 文献和实验
- 技术资料
- 抗体名:
ARG1 Antibody 抗体
- 抗体英文名:
ARG1 Antibody
- 靶点:
ARG1
- 浓度:
0.2 mg/mL
- 应用范围:
IF, IHC-P, WB
- 宿主:
Mouse
- 适应物种:
Human
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb1252048
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
Unconjugated
- 克隆性:
Monoclonal
- 保存条件:
详询
- 形态:
Liquid
- 亚型:
IgG3, kappa
- 免疫原:
详询
- 规格:
100 ug
类别: Antibodies
产品子类型: Primary Antibody
描述: ARG1 Antibody
克隆号: T1ARG-1
别名: Arginase-1, Liver-type arginase, Type I arginase, ARG1
应用说明: Immunofluorescence: 1-2 µg/mLWestern blot: 0.5-1 µg/mLImmunohistochemistry (FFPE): 2-4 µg/mL for 30 min at RT (1)Prediluted format : incubate for 30 min at RT (2)Optimal dilution of the Arginase 1 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
免疫原: A C-terminal recombinant protein fragment from ARG1 was used as the immunogen for the Arginase 1 antibody.
防腐剂: PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
纯化方法: Protein G affinity chromatography
研究领域: Metabolism Research, Signal Transduction
UniProt ID: P05089
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.


产品子类型: Primary Antibody
描述: ARG1 Antibody
克隆号: T1ARG-1
别名: Arginase-1, Liver-type arginase, Type I arginase, ARG1
应用说明: Immunofluorescence: 1-2 µg/mLWestern blot: 0.5-1 µg/mLImmunohistochemistry (FFPE): 2-4 µg/mL for 30 min at RT (1)Prediluted format : incubate for 30 min at RT (2)Optimal dilution of the Arginase 1 antibody should be determined by the researcher.1. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
免疫原: A C-terminal recombinant protein fragment from ARG1 was used as the immunogen for the Arginase 1 antibody.
防腐剂: PBS with 0.1 mg/ml rAlbumin and 0.05% sodium azide
纯化方法: Protein G affinity chromatography
研究领域: Metabolism Research, Signal Transduction
UniProt ID: P05089
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.

IHC testing of FFPE human hepatocellular carcinoma and Arginase 1 antibody.

Western blot testing of 1) partial recombinant ARG1 protein and 2) human liver lysate using Arginase 1 antibody.
风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验相关实验
连蛋白结合后抑制Syk信号通路,削弱其对肿瘤细胞的杀伤能力。在髓系细胞中,LILRB4通过招募SHP-1抑制巨噬细胞活化,降低TNF-α释放和吞噬功能;与Galectin-8结合后激活STAT3、抑制NF-κB,促进M-MDSC向免疫抑制表型极化,分泌ARG1和IL-10,进一步抑制T细胞功能,共同构建免疫抑制微环境。 LILRB4通过调控免疫耐受微环境促进免疫抑制。其在树突状细胞上高表达,诱导耐受性表型,减少CD80/CD86表达并促进Treg分化。作为抗原捕获受体,参与APCs信号整合,调节适应性免疫
技术资料暂无技术资料 索取技术资料
ARG1 Antibody 抗体,orb1252048,Biorbyt
¥13338






