- ￥1192 - 7000
- TargetMol
- TMA0984
- 2026年07月07日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- CAS号：
516-37-0
- 规格：
1mg/5mg/10mg/25mg
| 规格： | 1mg | 产品价格： | ￥1192.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥3304.0 |
| 规格： | 10mg | 产品价格： | ￥4704.0 |
| 规格： | 25mg | 产品价格： | ￥7000.0 |
Product Introduction
Bioactivity
| 名称 | Cerevisterol |
| 描述 | Cerevisterol is a cytotoxic steroid, can inhibit the activity of DNA polymerase alpha. It can stimulate NGF-mediated neurite outgrowth on PC12 cells. Cerevisterol acts as a natural agent for treating inflammatory diseases by targeting an MAPK, NF-κB, AP-1, and Nrf2-mediated HO-1 signaling cascade. |
| 体外活性 | Cerevisterol通过抑制LPS诱导的NO和PGE2产生来发挥作用，其机制可能是通过降低iNOS和COX-2的表达。同时，Cerevisterol还能减少如TNF-α、IL-6和IL-1β等促炎细胞因子的表达。Cerevisterol阻断了NF-κB的核内转移，其机制是通过阻止抑制性蛋白κBα（IκBα）的磷酸化和抑制NF-κB的转录激活作用。此外，Cerevisterol还抑制了丝裂原激活蛋白激酶（MAPK）信号通路，并抑制了AP-1的转录激活和c-Fos的磷酸化。Cerevisterol还能通过下调Kelch-like ECH相关蛋白1（Keap-1）和上调血红素氧合酶-1（HO-1）的表达，促进核因子红细胞相关因子2（Nrf2）的核内转移。 |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 关键字 | steroid | RNASynthesis | RNA Synthesis | NGF | Inhibitor | inhibit | fruiting bodies | DNASynthesis | DNA/RNA Synthesis | DNA Synthesis | Cerevisterol | Agaricus blazei |
| 相关产品 | Carbazole | Hexane-1,6-diol | Guanidine hydrochloride | Vidarabine | 1,4-Naphthoquinone | 5-Fluorouracil | Usnic Acid | Adenine hemisulfate | Erythromycin thiocyanate | Adenine | Docosanoic acid | Thymidine |
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Yeast Cell Cycle by Flow Cytometry
and resuspend pellet in 0.5 ml 50mM Na citrate containing 0.1 mg/ml RNase A. Leave in 5 ml Falcon tube and put in 37 °C room for 2 h. For staining: Propidium Iodide Add 0.5 ml 50 mM Na citrate containing 8 µg/ml PI
label the plates and place them in an incubator for 24 hours at 37° C. 7. At the conclusion of incubation, remove each of the four petri plates and count the number of colonies formed on the plates. For proper statistical analysis, the plate containing
512.7 53.18 474.65～550.75 14 494.8 37.24 468.15～521.45 15 493.6 39.94 465.03～522.17 16 495.3 29.47 474.22～516.38 17
技术资料暂无技术资料 索取技术资料
