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- 2026年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- CAS号：
91-33-8
- 规格：
1mLx10mM(inDMSO)/100mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥265.0 |
|---|---|---|---|
| 规格： | 100mg | 产品价格： | ￥124.0 |
Product Introduction
Bioactivity
| 名称 | Benzthiazide |
| 描述 | Benzthiazide (Lemazide) is used in the therapy of edema and hypertension. Like other thiazides, benzthiazide accelerates water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue. |
| 存储条件 | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 50 mg/mL (115.76 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (11.58 mM), Solution. 10% DMSO+90% Saline : < 5 mg/mL (11.58 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| 关键字 | Inhibitor | inhibit | CarbonicAnhydrase | Carbonic anhydrase | Carbonate dehydratase | Benzthiazide |
| 相关产品 | Urea | Cyclamic acid sodium | 2-Methoxy-4-propylphenol | Benzenesulfonamide | Acesulfame | Zonisamide | Sodium Dihydrogen Phosphate | pNNP | Tioxolone | Fluorometholone Acetate | Orthanilamide | Hydrochlorothiazide |
| 相关库 | Inhibitor Library | Anti-Cancer Approved Drug Library | Anti-Cancer Active Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max | Anti-Cancer Metabolism Compound Library | ReFRAME Related Library | FDA-Approved & Pharmacopeia Drug Library | Approved Drug Library | FDA-Approved Drug Library | Drug Repurposing Compound Library | Anti-Cancer Drug Library |
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文献和实验3.61 3.38 3.22 3.10 3.00 2.93 2.87 2.77 2.67 2.56 2.44 2.32 2.19 18 19 4.51 3.90 3.56 3.33 3.17 3.05 2.96 2.88 2.82 2.72 2.62 2.51 2.39 2.27 2.13 19 20 4.46 3.86 3.51 3.29 3.13 3.01 2.91 2.84 2.77 2.68 2.57 2.46 2.35 2.22 2.08 20 21 4.42
78 87 35 20 96 43 84 26 34 91 64 7 84 42 17 53 31 57 24 55 06 88 77 04 74 47 67 21 76 33 50 25 83 92 12 06 76 8 63 01 63 78 59 16 95 55 67 19 98 10 50 71 75 12 86 73 58 07 44 39 52 38 79 9 33 21 12 34 29 78 64 56 07 82 52 42 07 44 38 15 51 00 13 42
2.96 2.94 9 10 4.96 4.10 3.71 3.48 3.33 3.22 3.14 3.07 3.02 2.98 2.91 2.86 2.83 2.80 2.77 10 11 4.84 3.98 3.59 3.36 3.20 3.09 3.01 2.95 2.90 2.85 2.79 2.74 2.70 2.67 2.65 11 12 4.75 3.89 3.49 3.26 3.11 3.00 2.91 2.85 2.80 2.75 2.69 2.64 2.60 2.57
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