- ￥146 - 2784
- TargetMol
- T5788
- 2026年07月07日
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- 详细信息
- 文献和实验
- 技术资料
- CAS号：
6860-47-5
- 规格：
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mg | 产品价格： | ￥146.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥287.0 |
| 规格： | 5mg | 产品价格： | ￥278.0 |
| 规格： | 10mg | 产品价格： | ￥430.0 |
| 规格： | 25mg | 产品价格： | ￥856.0 |
| 规格： | 50mg | 产品价格： | ￥1264.0 |
| 规格： | 100mg | 产品价格： | ￥1880.0 |
| 规格： | 200mg | 产品价格： | ￥2784.0 |
Product Introduction
Bioactivity
| 名称 | XYLOBIOSE |
| 描述 | XYLOBIOSE ia a natural product,and exhibited therapeutic potential for treating obesity which involved suppression of fat deposition and obesity-related metabolic disorders. |
| 动物实验 | The mice were randomized into five groups: (a) a control group (Ctrl, n = 10) which received a diet of modified American Institute of Nutrition (AIN)-93G (17% of the calories are from fat); (b) a high fat diet (HFD)-induced obesity control group (HF, n = 13) which received a HFD comprised of 60% fat; (c) a xylose 15% group (Xylo 15) which received a HFD with 15% of the total sucrose replaced with d-xylose (n = 13); (d) an XYLOBIOSE 10% group (XYLOBIOSE 10, n = 13) which received a HFD with 10% of the total sucrose replaced by XYLOBIOSE; and (e) an XYLOBIOSE 15% group (XYLOBIOSE 15, n = 12) which received a HFD with 15% of the total sucrose replaced by XYLOBIOSE. Commercially available D-xylose was included as a positive control and was administered at a dose comparable to XYLOBIOSE. The mice were maintained on these diets according to their group for ten weeks prior to sacrifice. Body weight and food intake were measured twice a week. |
| 体内活性 | 小鼠接受含60%高脂饮食，其中包含15%的d-xylose、10%或15%的XYLOBIOSE，作为总蔗糖含量的一部分，持续十周。XYLOBIOSE补充显著降低了体重、脂肪和肝脏重量、空腹血糖以及血脂水平。同时，XYLOBIOSE补充还改善了瘦素和脂肪细胞因子水平，并且在网膜脂肪和肝脏中调低了脂肪生成和脂肪细胞生成基因的表达。此外，XYLOBIOSE补充还降低了网膜脂肪中的促炎细胞因子、脂肪酸摄取、脂解作用和β-氧化相关基因的表达水平[1]。XYLOBIOSE通过调节miR-122a/33a轴，在db/db小鼠中展示了抗糖尿病、降脂和抗炎的效果[2]。 |
| 存储条件 | Keep away from direct sunlight,Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+90% Saline : 10 mg/mL (35.43 mM), Solution. DMSO : 250 mg/mL (885.77 mM), Sonication is recommended. |
| 关键字 | XYLOBIOSE | TNF-α | Inhibitor | inhibit | ILReceptor | IL-1β | IL Receptor | Disaccharide |
| 相关产品 | Mequinol | Kaolin | Ethyl palmitate | 1,4-Naphthoquinone | Palmitic acid sodium | Glucosamine | Gum arabic | Palmitic acid | Tributyrin | Ethoxyquin | Tamoxifen | 1,8-Cineole |
| 相关库 | Microbial Natural Product Library | Bioactive Compound Library | Selected Plant-Sourced Compound Library | Bioactive Compounds Library Max | Anti-Alzheimer's Disease Compound Library | Anti-Tumor Natural Product Library | Anti-Aging Compound Library | Cosmetic Ingredient Compound Library | Natural Product Library | Immunology/Inflammation Compound Library | Saccharide and Glycoside Natural Product Library | Natural Product Library for HTS |
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文献和实验˚05΄，北纬34º19'～36º16。其范围为昆仑山脉以南，乌兰乌拉山以北，东起青藏公路，西迄省界。保护区西与西藏自治区相接，南同格尔木唐古拉乡毗邻，北和新疆维吾尔族自治区相连，东至青藏公路，总面积4.5万平方公里。 可可西里地处青藏高原腹地，平均海拔在4600米以上，最高峰为北缘昆仑山布喀达板峰(亦称新青峰或莫诺马哈峰)，海拔6860米；最低点在豹子峡(昆仑山南鹿红水河横穿博卡雷克拐弯处)，海拔4200米。区内地势南北高，中部低，西部高而东部低。可可西里山和冬布勒山横贯本区中部
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