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- 详细信息
- 文献和实验
- 技术资料
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
-20°C
- 克隆性:
单克隆
- 适应物种:
Mouse
- 保质期:
twelve months
- 级别:
一抗
- 供应商:
武汉益普生物科技有限公司
- 宿主:
Hamster
- 抗体英文名:
InVivoMAb Anti-Mouse CD3E Antibody (145-2C11)
- 规格:
100μg/1mg
| 规格: | 100μg | 产品价格: | ¥2288.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥9188.0 |
| 产品名 | InVivoMAb Anti-Mouse CD3E Antibody (145-2C11) |
| 货号 | MY057400 |
| 宿主 | Hamster |
| 种属反应性 | Mouse |
| 描述 | 145-2C11 is highly effective at inducing T-cell depletion in vivo. In BALB/c mice, administration of 145-2C11 resulted in a marked reduction of circulating T cells, even at very low doses. A single injection of just 1 μg was sufficient to significantly diminish T-cell levels, while higher doses of 20 μg and 100 μg produced even more profound and extensive depletion. These properties make 145-2C11 a powerful experimental tool for modulating T-cell responses and studying immune regulation in murine models. |
| 克隆类型 | Monoclonal |
| 克隆号 | 145-2C11 |
| Accession号 | P07766 |
| 靶标 | T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain, CD3e, CD3E, T3E |
| 同种型 | IgG |
| 应用 | FCM, ICC, IHC, IP, T cell stimulation (Reported), T cell depletion (Reported), WB |
| 内毒素水平 | < 10 EU/mg |
| 纯化方式 | Protein A/G purified from cell culture supernatant. |
| 纯度 | >95% as determined by SDS-PAGE. |
| 状态 | Liquid |
| 保存溶液 | 0.01M PBS pH 7.4 |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 说明 | For research use only. |

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文献和实验proliferation. What You Need Materials 1X sterile PBS Anti-mouse CD3e, 145-2C11: Functional Grade, Cat. No. 16-0031 , or Purified, Cat. No. 14-0031 Supplemented RPMI-1640 click
T-Cell Activation Using mAb to CD3
splenic T-cells and human peripheral T cells stimulated via CD3. Critical parameters include cell density, antibody titer and activation kinetics. Materials 1X sterile PBS Anti-mouse CD3e, Clone 145-2C11 (Functional Grade, Cat. No. 16
Th17 Polarization of Mouse CD4 Cells
实验试剂 Sterile PBS Cell culture medium Sterile plastic petridishes RBC Lysis Buffer [Details: Biolengend, cat.#420301] Anti-mouse CD3ε, clone145-2C11[Details: LEAF™format, cat.#100314]
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