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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
武汉研升生物科有限公司
- 检测范围:
0.16-10 ng/mL
- 检测方法:
Sandwich
- 适应物种:
Rat
- 样本:
Tissue homogenates and other biological fluids.
- 灵敏度:
0.049 ng/mL
- 规格:
48T/96T
| 规格: | 48T | 产品价格: | ¥1820.0 |
|---|---|---|---|
| 规格: | 96T | 产品价格: | ¥2600.0 |
| 中文名称 | 大鼠干扰素调节因子7(IRF7)酶联免疫吸附检测试剂盒 |
| 英文名称 | Rat IRF7(Interferon Regulatory Factor 7) ELISA Kit |
| 别名 | Interferon regulatory factor 7; IRF-7; IRF7 |
| 货号 | ELK9745 |
| 反应种属 | Rat |
| 检测类型 | Sandwich |
| 灵敏度 | 0.049 ng/mL |
| 标准品 | 10 ng/mL |
| 检测范围 | 0.16-10 ng/mL |
| 样本类型 | Tissue homogenates and other biological fluids. |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat IRF7. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat IRF7. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Rat IRF7, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat IRF7 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Immune molecule; |

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文献和实验「七分饱」抗衰老又添科学证据!研究揭示限制饮食可改善由衰老引起的炎症反应
Reports 饮食限制可抑制衰老诱导的干扰素反应 在哺乳动物中,干扰素保护宿主免受病毒和非病毒病原体的侵害,Ifn 基因的转录启动依赖于对致病信号的识别,这可导致 Irf 转录因子家族的激活。他们也发现,Irf1、Irf3 和 Irf7 在衰老过程中被激活,而 DR 则可抑制这种活化状态。这些转录因子也通过组织和条件特异性的方式进行转录调控。例如,在肝脏中,Irf1 在 STDR 中显著下调,Irf3 在 LTDR 中显著下调,Irf7 则在肝脏、血液和肾脏中表达最多,并在衰老过程中显著上调
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