小鼠细胞因子信号转导抑制因子1(SOCS1)酶联免疫吸附检测
试剂盒【Mouse SOCS1(Suppressors Of Cytokine Signaling 1) ELISA Kit】- ￥1960 - 2800
- ELK Biotechnology
- 0.32-20 ng/mL
- 0.116 ng/mL
- 武汉
- ELK9422
- 2026年04月25日
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
武汉研升生物科有限公司
- 检测范围：
0.32-20 ng/mL
- 检测方法：
Sandwich
- 适应物种：
Mouse
- 样本：
Tissue homogenates, cell lysates and other biological fluids.
- 灵敏度：
0.116 ng/mL
- 规格：
48T/96T
| 规格： | 48T | 产品价格： | ￥1960.0 |
|---|---|---|---|
| 规格： | 96T | 产品价格： | ￥2800.0 |
| 中文名称 | 小鼠细胞因子信号转导抑制因子1(SOCS1)酶联免疫吸附检测试剂盒 |
| 英文名称 | Mouse SOCS1(Suppressors Of Cytokine Signaling 1) ELISA Kit |
| 别名 | CIS1; CISH1; JAB; SOCS-1; SSI-1; SSI1; TIP3; JAK-binding protein; STAT-induced STAT inhibitor 1; Tec-interacting protein 3 |
| 货号 | ELK9422 |
| 反应种属 | Mouse |
| O35716 | O35716 |
| 检测类型 | Sandwich |
| 灵敏度 | 0.116 ng/mL |
| 标准品 | 20 ng/mL |
| 检测范围 | 0.32-20 ng/mL |
| 样本类型 | Tissue homogenates, cell lysates and other biological fluids. |
| 反应时间 | 3.5h |
| 检测原理 | The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse SOCS1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse SOCS1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Mouse SOCS1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Mouse SOCS1 in the samples is then determined by comparing the OD of the samples to the standard curve. |
| 研究领域 | Immune molecule; |
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文献和实验is turned off by proteins termed suppressors of cytokine signaling (SOCS) (3 ). As the nomenclature indicates, this class of polypeptides has the capacity to interfere and silence other cytokine-induced signaling cascades (for review see (4 )). SOCS1
-κB信号通路受到抑制时，炎症反应和肿瘤都不回发生。 研究过程中，需要观察NF-κB信号通路受抑制情况下，各种细胞因子表达水平的变化，本文采用了Superarray的小鼠细胞因子基因芯片（GEArray Q Series Mouse Common Cytokine Gene Array， Catalog No. MM-003N）进行检测。 Caner Research 2004 Apr 1;64(7):2469-73. Differential gene expression
上包含的基因可编码上述信号通路中的粘附分子、受体、配体、接头蛋白、调控因子、转录因子、激酶及下游效应蛋白。信号转导在免疫细胞激活、增殖、分化和凋亡中扮演了重要的角色，而这些生物学过程也与许多重要的病理及生理免疫反应有关，如：抗病毒反应、自身免疫、过敏症、炎症，及免疫缺陷。 基因列表(Functional Gene Grouping): AKT and PI3K Family Members and Their Regulators: AKT1, AKT2, AKT3, APPL, BTK
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