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文献和实验Primer Design(Manual and Automated Primer Design for SEQ and PHY Gaps)
Length: 18 to 21 nucleotides Tm 56-60℃ 4+2 Rule:Tm = (#G + #C) x 4 + (#A + #T) x 2 Inside the clone Designing PCR Primers for Physical Ends Length: 24 to 28 nucleotides
A Hepatitis C Virus Xenograft Mouse Efficacy Model
The lack of a robust small-animal model for hepatitis C virus (HCV) has hindered the discovery and development of novel drug treatments for HCV infections. We developed a reproducible and easily accessible xenograft mouse efficacy model
Whole-Animal High-Throughput Screens: The C. elegans Model
-interference (RNAi) methodology, C. elegans is the only metazoan in which the impact of “knocking-down” nearly every gene in the genome can be analyzed in a whole living animal. Both functional genomic studies and chemical screens can be carried out using C
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