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- 详细信息
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- 供应商:
苏州瑞诺德生物科技有限公司
- 规格:
100 µl
抗体
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文献和实验Probing the Telomere Damage Response
to the activation of DNA damage checkpoint sensors, including the Mre11-Rad50-Nbs1 (MRN) complex, γ-H2AX and 53BP1, the ATM and ATR signal-transducing kinases and downstream effectors, including Chk1, Chk2, and p53. Robust DNA damage response signals
Analysis of Cell Cycle Progression and Genomic Integrity in Early Lethal Knockouts
Owing to their importance in normal cell division, DNA damage checkpoint and repair genes are often required for the earliest stages of embryonic development. For example, conventional deletion of ATR (1 ), Chk1 (2 ), Mad2 (3 ), NBS (4 ), Rad50
Multicolor Laser Scanning Confocal Immunofluorescence Microscopy of DNA Damage Response Biomarkers
and maintain the spatial information. Here we describe the experimental protocols to quantify individual key events of the DDR cascade in three-dimensionally preserved nuclei by LSCIM with high resolution, using the simultaneous detection of Rad50
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