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CD223 Antibody, anti-mouse, AP

C, REAfinity™, 150 µg in 1 mL
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  • 询价
  • Miltenyi Biotec已认证
  • 德国
  • 130-111-328
  • 2025年12月09日
  • Flow cytometry
  • human cell line
  • mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 免疫原

      CD223

    • 亚型

      recombinant human IgG1

    • 形态

      Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.

    • 保存条件

      避光,4-8℃

    • 克隆性

      REA776

    • 标记物

      APC

    • 适应物种

      mouse

    • 保质期

      24个月

    • 供应商

      Miltenyi Biotec

    • 宿主

      human cell line

    • 应用范围

      Flow cytometry

    • 浓度

      1:50

    • 抗体英文名

      CD223 Antibody, anti-mouse, REAfinity™

    • 抗体名

      CD223 Antibody, anti-mouse, REAfinity™

    • 规格

      150 µg in 1 mL

    Identification and enumeration of CD223+ cells by flow cytometryClone REA776 recognizes an epitope within the D2 domain of murine CD233, also known as LAG-3, which is a 70 kDa high affinity MHC class II ligand. It is expressed on activated CD4+ and CD8+ α/β T cells, on a subset of NK cells, B cells and plasmacytoid dendritic cells. It is proposed, that LAG-3 could be used as a marker of T cell induced B cell activation. | In association with the CD3 complex CD223 is a negative regulatory molecule to inhibit TCR-mediated signaling and to regulate homeostatic T cell expansion. | Additional information: Clone REA776 displays negligible binding to Fc receptors

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    图标文献和实验
    该产品被引用文献
    Baixeras, E. et al. (1992) Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens. J. Exp. Med. 176 (2): 327–337. | Workman, C. J. et al. (2002) Phenotypic analysis of the murine CD4-related glycoprotein, CD223 (LAG-3). Eur. J. Immunol. 32 (8): 2255–2263. | Workman, C. J. et al. (2002) Cutting edge: Molecular analysis of the negative regulatory function of lymphocyte activation gene-3. J Immunol 169 (10): 5392–5395. | Kisielow, M. et al. (2005) Expression of lymphocyte activation gene 3 (LAG-3) on B cells is induced by T cells. Eur. J. Immunol. 35 (7): 2081–2088.
    相关实验
    • AbC Anti-Mouse Bead Kit

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    • CD3/CD28 做好 T 细胞激活与扩增

      7211011 小鼠淋巴细胞分离液 达优 100339 Ultra-LEAF Purified anti-mouse CDAntibody BioLegend 102115 Ultra-LEAF Purified anti-mouse CD28 Antibody BioLegend   CD3/CD28 Streptamer® 多聚体法:   货号 名称

    • Th17 Polarization of Mouse CD4 Cells

      of anti-mouse CD28, clone 37.51(5μg/mL),IL-6 (50ng/mL),TGF-β1 (1ng/mL), anti-mouse IL-4 (10μg/mL), anti-mouse IFN-γ (10μg/mL), and 300 nM of FICZ. Alternatively, mouse IL-23 (5ng/ ml) can be used in place of FICZ. 3)        On day

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    CD223 Antibody, anti-mouse, APC, REAfinity™, 150 µg in 1 mL
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