HCCLM3细胞

HCCLM3 /HCCLM3 细胞系/HCCLM3 细胞株/HCCLM3 人高转移肝癌细胞

Cell line name HCCLM3

Synonyms HCCLM-3; HCC-LM3; LM3; MHCC-LM3; MHCCLM3

Accession CVCL_6832

Secondary accession CVCL_7679

Resource Identification Initiative To cite this cell line use: HCCLM3 (RRID:CVCL_6832)

Comments Population: Chinese.

Characteristics: Established from pulmonary metastatic lesions produced in nude mice by 3 rounds of subcutaneous inoculation of parent cell line (PubMed=12133480).

Doubling time: 34.9 hours (PubMed=12133480).

Karyotypic information: Has lost chromosome Y.

Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).

Omics: Transcriptome analysis by microarray.

PubMed=12133480

Li Y., Tang Z.-Y., Ye S.-L., Liu Y.-K., Chen J., Xue Q., Huang X.-W., Chen J., Bao W.-H., Yang J., Gao D.-M.

Establishment of human hepatocellular carcinoma cell line with spontaneous pulmonary metastasis through in vivo selection.

Zhonghua Yi Xue Za Zhi 82:601-605(2002)

 

PubMed=12618900; DOI=10.1007/s00432-002-0396-4

Li Y., Tang Y., Ye L., Liu B., Liu K., Chen J., Xue Q.

Establishment of a hepatocellular carcinoma cell line with unique metastatic characteristics through in vivo selection and screening for metastasis-related genes through cDNA microarray.

J. Cancer Res. Clin. Oncol. 129:43-51(2003)

 

PubMed=15796966; DOI=10.1016/j.cancergencyto.2004.05.010

Yang J., Qin L.-X., Li Y., Ye S.-L., Liu Y.-K., Gao D.-M., Chen J., Tang Z.-Y.

Molecular cytogenetic characteristics of the human hepatocellular carcinoma cell line HCCLM3 with high metastatic potential: comparative genomic hybridization and multiplex fluorescence in situ hybridization.

Cancer Genet. Cytogenet. 158:180-183(2005)

 

PubMed=19335983; DOI=10.3760/cma.j.issn.1007-3418.2009.03.010

Zheng D., Liu B.-B., Liu Y.-K., Kang X.-N., Sun L., Guo K., Sun R.-X., Chen J., Zhao Y.

Analysis of the expression of Slit/Robo genes and the methylation status of their promoters in the hepatocellular carcinoma cell lines.

Zhonghua Gan Zang Bing Za Zhi 17:198-202(2009)

 

PubMed=32884988; DOI=10.1016/j.gendis.2019.12.008; PMCID=PMC7452459

Lin Y.-L., Li Y.

Study on the hepatocellular carcinoma model with metastasis.

Genes Dis. 7:336-350(2020)