- ￥4329 - 8775
- Biorbyt
- orb1823520
- 英国
- 2026年08月06日
- IHC-P
- Rabbit
- Human
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- 文献和实验
- 技术资料
- 抗体名：
p40 Antibody / deltaNp63 抗体
- 抗体英文名：
p40 Antibody / deltaNp63
- 应用范围：
IHC-P
- 宿主：
Rabbit
- 适应物种：
Human
- 保质期：
12 months from date of receipt.
- 抗原来源：
详询
- 目录编号：
orb1823520
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
Recombinant
- 保存条件：
详询
- 亚型：
Rabbit IgG, kappa
- 免疫原：
详询
- 规格：
20 ug/100 ug
| 规格： | 20 ug | 产品价格： | ￥4329.0 |
|---|---|---|---|
| 规格： | 100 ug | 产品价格： | ￥8775.0 |
产品子类型: Primary Antibody
描述: p63 consists of two major isoforms-TAp63 and delta-Np63. These isoforms differ in the structure of the N-terminal domains. The TAp63 isoform (identified by anti-p63 antibody) contains a transactivation-competent TA domain with homology to p53, which regulates the expression of the growth-inhibitory genes. In contrast, DNp63 isoform (identified by anti-p40 antibody) contains an alternative transcriptionally-inactive delta-N domain, which antagonizes the activity of TAp63 and p53. The p40 (clone P40/8225R) antibody recognizes exclusively delta-Np63 but not TAp63. p40 is a squamous cell carcinoma specific antibody. It reacts with the vast majority of cases of squamous cell carcinomas of various origins, but not with adenocarcinomas. It is particularly useful in differentiating lung squamous cell carcinoma from lung poorly differentiated adenocarcinoma. p40 antibody can also be used as an alternative basal cell/myoepithelial cell marker, which has similar sensitivity and specificity as that of p63 antibody. Therefore, p40 antibody may also be used as an alternative immunohistochemical marker for determining prostate adenocarcinoma vs. benign prostate glands and for determining breast intraductal carcinoma vs. invasive breast ductal carcinoma.
克隆号: P40/8225R
应用稀释比例: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
应用说明: Optimal dilution of the p40 antibody should be determined by the researcher.
免疫原: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the p40 antibody.
防腐剂: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
纯化方法: Protein A affinity
UniProt ID: Q9H3D4
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
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文献和实验secondary antibody review -- data from 99 publications
cytometry used as a control to detect cell responses targeted antigen 7 Alexa Fluor 488 7 Cy3 8 goat IgG Alexa Fluor 488 1:2000 detect antibody binding in human embryonic kidney 293T cells Invitrogen 9 donkey
The production of monoclonal antibody by hybridoma
transfer into 95 ml of Clonacell Medium D (HAT) media (with 5 ml of HCF) and plate out 10 ml per small petri plate. 14. Dilute about 1000 P3X63 Ag8.653 myeloma cells into 1 ml of mediu D and transfer into a single well of a 24
) (HY-P80983) www.medchemexpress.cn/antibody/cdx2-antibody.html 兔来源、无偶联标记、抗 CDX2 的 IgG 单克隆抗体。 p63 Antibody (YA1531) (HY-P81786) www.medchemexpress.cn/antibody/p63-antibody-ya1531.html 兔来源、无偶联标记、抗 p63 的 IgG 单克隆抗体。 FOLR1 Antibody (YA1099) (HY-P
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