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文献和实验Expression and Dimerization of Hepatitis C Virus Core Protein in E. coli
Hepatitis C virus (HCV) is a positive-stranded RNA virus with a genome size of about 9–10 kb. The genome of this virus encodes a polyprotein with a length of over 3000 amino acids. This polyprotein is cleaved by cellular and viral proteases
Nomenclature and Numbering of the Hepatitis C Virus
International standardization and coordination of the nomenclature of variants of hepatitis C virus (HCV) is increasingly needed as more is discovered about the scale of HCV-related liver disease and important biological and antigenic
Adaptation of the Hepatitis C Virus to Cell Culture
A major breakthrough in the field of HCV research was the development of a system that supports the production of infectious virus particles. The key to this achievement was the molecular cloning of a genotype 2a genome, designated JFH
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