介质脱气或“脱气”,预热至37°C以及根据绝对精确重量分配的建议和美国FDA当局对溶出度测试规定是Pharma Test PT-DDS4介质制备和脱气系统的标准。 通常建议进行除气,以防止在剂型表面上形成气泡,由于表面不透明,气泡可能导致活性溶出速率发生变化。
产品优势:
PT-DDS4容器内的残余氧低于5 ppm
预加热介质,以节省溶解试验启动期间的时间
在压力下填充程序(直接连接到工厂de-min.供水)
真空下加注程序(从任何外部容器加注)
易于控制,清洗方便
产品特点:
同时对约24升介质进行脱气和加热
介质预热;目标温度可在30–50℃之间调节
可调重量计量范围:250–5000g
LCD显示屏和键盘,用于显示和输入数据
最小处理量1L
内置热敏打印机,用于报告给药介质的重量或体积,并记录调整和校准结果
The preparation and degassing of the medium is an important part of the tablet dissolution test, because the degassed medium is very important for the reproducibility of the dissolution results. Media degasing or “de-aeration”, pre-heating to a temperature of 37°C and absolutely precise gravimetric dispensing according to the recommendations and demanded for dissolution testing from the US FDA authorities are standard for the Pharma Test PT-DDS4 media preparation and degasing system. De-aeration is generally recommended to prevent the formation of bubbles on the dosage form surface, which may cause a variation in active dissolution rates, by virtue of surface obscuration. 1.residual oxygen less than 5 ppm inside PT-DDS4 container 2.Pre-heats your media to save time during start-up of dissolution tests 3.Fill-up program under pressure (connect directly to factory de-min. water supply) 4.Fill-up program under vacuum (prime from any external container) 5.Good access to the media tank, easy to control the cleaning and test procedure