Kifunensine was originally isolated from the actinomycete Kitasatosporia kifunensine No. 9482 and shown to be a weak inhibitor of aryl mannosidase.{14697,14696} It has since been shown to be a potent and selective inhibitor of class I α-mannosidases and
英文名:
FR900494
库存:
1 mg, 10 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
109944-15-2
规格:
This biochemical is available in the following size(s) 100 µg, 50 µg, 500 µg - Please inquire
A potent and selective inhibitor of class I α-mannosidases and serves as a key inhibitor of glycoprotein biosynthesis; inhibits both human ER α-1,2-mannosidase I and Golgi class I mannosidases (Golgi α-mannosidase IA, IB, and IC) exhibiting Ki values of 130 and 23 nM, respectively; inhibits mung bean α-1,2-mannosidase I with an IC50 value of 20-50 nM