美国Matreya LLC提供的是为甲酯,是理想的气相色谱标准品.溶解于氯仿,乙醇,正己烷,甲醇.反十,顺十二,十八碳二烯酸是共轭亚油酸(CLA),亚油酸的异构体。美国Matreya LLC致力于开发和制造高质量和高价值的脂类和生物化学品.美国Matreya LLC在化学合成和天然产品的提取和纯化方面的经验使Matreya LLC能够使用专有技术达到最佳的纯度.美国Matreya LLC的产品线包括广泛的鞘脂类,糖脂类,糖鞘脂类,脂肪酸和酯类,甾醇和维生素E异构体(生育酚和生育三烯醇). 美国Matreya LLC的专长是生产高纯度的鞘氨脂,神经酰胺,硫化物,球形三酰神经酰胺,神经节苷脂,酶抑制剂,生育酚和生育三烯醇. 在鞘脂领域,Matreya LLC已经赢得了作为问题解决者和技术的声誉,由于Matreya LLC专注度.
Specifications
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Catalog #:1249
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Scientific Name:10(E),12(Z)-Octadecadienoic acid
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Common Name:10 trans, 12 cis-CLA
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Empirical Formula:C18H32O2
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CAS#:2420-56-6
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SDS:View Safety Data Sheet
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Data Sheet:View Data Sheet
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Formula Weight:280
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Unit:25 mg
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Solvent:none
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Source:synthetic
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Purity:98+%
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Analytical Methods:GC, TLC, identity confirmed by MS
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Solubility:ethanol,methanol,hexane,chlorofom
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Physical Appearance:liquid
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Storage:-20℃
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Dry Ice:No
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Hazardous:No
Application Notes:
10(E),12(Z)-十八碳二烯酸是共轭亚油酸(CLA),亚油酸的异构体。共轭亚油酸主要存在于反刍动物的脂质中,包括乳制品。它具有多种生物学特性,包括抗癌活性,抑制人体黑色素瘤、结直肠癌和乳腺癌细胞的体外生长,并表现出抗动脉粥样硬化活性人们认为CLA本身可能不具有抗氧化能力,但可能产生保护细胞免受过氧化物伤害的物质。已观察到饲料中含有高水平共轭亚油酸的动物提高了饲料效率(瘦体质量增加而体脂肪减少),这似乎主要或完全是由于10(E),12(Z)-十八碳二烯酸然而,这种异构体似乎会增加肥胖男性的氧化应激和炎症生物标志物,从而导致胰岛素抵抗。3,4,10 (E),12(Z)-十八碳二烯酸增加人体的低密度脂蛋白:高密度脂蛋白胆固醇和总高密度脂蛋白胆固醇。
10(E),12(Z)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals, including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. Animals fed a diet containing high levels of CLA have been observed to have improved feed efficiency (lean body mass increased while body fat decreased) and this seems to be due, mainly or exclusively, to the 10(E),12(Z)-Octadecadienoic acid.2 However, this isomer appears to increase oxidative stress and inflammatory biomarkers in obese men, which can lead to insulin resistance.3,4 10(E),12(Z)-Octadecadienoic acid increases LDL:HDL cholesterol and total:HDL cholesterol in humans.
References:
1. Helen B. MacDonald, Journal of the American College of Nutrition, Vol. 19, No. 90002, 111S-118S, 2000
2. Yanwen Wang and Peter J. H. Jones, The American Journal of Clinical Nutrition, June, Vol. 79, No. 6, 1153S-1158S, 2004
3. Ulf Risérus, MMed, Samar Basu, PhD; Stefan Jovinge, MD, PhD; Gunilla Nordin Fredrikson, PhD; Johan Ärnlöv, MD; Bengt Vessby, MD, PhD, Circulation, 106:1925, 2002
4. Soonkyu Chung, J. Mark Brown, J. Nathan Provo, Robin Hopkins and Michael K. McIntosh, The Journal of Biological Chemistry, September, Vol. 280: 38445, 2005
Matreya,LLC是一家油脂生化公司,提供综合系列的鞘脂、糖脂、神经节苷脂、球三糖神经酰胺、脂肪酸和甾醇。我们在高纯度产品和专门的技术援助方面享有可靠的声誉。 Matreya致力于开发和制造的脂质和生化物质。我们提供高质量的化学合成和天然产物的提取和纯化。惠诚生物把Matreya已经引入到国内市场,大量现货销售及产品服务。 10(E),12(Z)-Octadecadienoic acid is a conjugated linoleic acid (CLA), an isomer of linoleic acid. CLA is found mostly in lipids originating in ruminant animals, including dairy products. It has several biological properties including anticarcinogenic activity, suppressing in vitro growth of human melanoma, colorectal, and breast cancer cells, and exhibiting anti-atherogenic activity.1 It is thought that CLA itself may not have anti-oxidant capabilities but may produce substances which protect cells from the detrimental effects of peroxides. Animals fed a diet containing high levels of CLA have been observed to have improved feed efficiency (lean body mass increased while body fat decreased) and this seems to be due, mainly or exclusively, to the 10(E),12(Z)-Octadecadienoic acid.2 However, this isomer appears to increase oxidative stress and inflammatory biomarkers in obese men, which can lead to insulin resistance.3,4 10(E),12(Z)-Octadecadienoic acid increases LDL:HDL cholesterol and total:HDL cholesterol in humans.
上海惠诚生物专业优势供应Matreya磷脂类标准品 ,每周三和国外下单,2周到货。
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