Have you heard someone to study miRNAs in Bacteriophage? Which should not be bigger than virus.
The reason is that siRNA and miRNA need some protein complex such as Dicer and Ago encoded by eukaryote to function. These genes have not be identified in bacterial, so it's currently believed there are no siRNA and miRNA in bacterial and Bacteriophage.
alixtardxy wrote: Have you heard someone to study miRNAs in Bacteriophage? Which should not be bigger than virus.
The reason is that siRNA and miRNA need some protein complex such as Dicer and Ago encoded by eukaryote to function. These genes have not be identified in bacterial, so it's currently believed there are no siRNA and miRNA in bacterial and Bacteriophage.
Small RNAs in bacteria are totally different from siRNAs and miRNAs. In most cases, these small moleculars will interfere the binding of ribosomes to mRNA to inhibit translation.
alixtardxy wrote: Small RNAs in bacteria are totally different from siRNAs and miRNAs. In most cases, these small moleculars will interfere the binding of ribosomes to mRNA to inhibit translation.
alixtardxy wrote: Small RNAs in bacteria are totally different from siRNAs and miRNAs. In most cases, these small moleculars will interfere the binding of ribosomes to mRNA to inhibit translation.
我没有说清楚。 我说类似 miRNA只是指它们也是行使转录后抑制的功能,就像你说的那样。摘抄一点introduction:
"In recent years, hundreds of RNAs that do not encode proteins but have intrinsic functions as regulators have been identified. These RNAs are generally denoted noncoding RNAs in eukaryotes and small RNAs (sRNAs) in bacteria. In Escherichia coli alone, >70 sRNA genes have been identified. Those bacterial sRNAs whose functions have been characterized can be sorted into three general categories: sRNAs that have intrinsic catalytic activity or are components of ribonucleoproteins, sRNAs that affect protein activity by structurally mimicking other nucleic acids and sRNAs that post-transcriptionally regulate mRNAs via basepairing interactions"