THEAFLAVIN-3,3’-DIGALLATE

Description Theaflavin-3,3’-digallate is a polyphenolic compound found in black tea. The theaflavins are formed during the enzymatic oxidation of catechins, which happens during processing of the fresh tea leaves. Theaflavin-3,3’-digallate has also shown inhibitory effects on ovarian cancer cells OVCAR-3 and A2780/CP70 by inducing apoptosis and impairing tumor angiogenesis. In addition, theaflavin-3,3’-digallate was found to produce notably efficient reactive oxygen species scavenging activity by a chemiluminescence assay. Theaflavin-3,3’-digallate was also shown to produce chemopreventive effects through the inhibition of the EGFR signaling pathway as a result of EGFR down-regulation. Product Info
Cas No. 30462-35-2
Purity ≥98%
Formula C43H32O20
Formula Wt. 868.71
Chemical Name [(2R,3R)-2-[1-[(2R,3R)-5,7-Dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,5-trihydroxy-6-oxobenzo[7]annulen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
IUPAC Name (3,4,5-Trihydroxy-6-oxo-6H-benzo[7]annulene-1,8-diyl)bis[(2R,3R)-5,7-dihydroxy-3,4-dihydro-2H-chromene-2,3-diyl] bis(3,4,5-trihydroxybenzoate)
Synonym Theaflavin digallate
Melting Point 226-230°C dec
Solubility 0.1 mg/mL water.
Appearance Brick red powder