植物表达的新药ZMapp——抗埃博拉病毒有奇效
美国马普生物制药公司研发的新药ZMapp，治愈了全部18只感染埃博拉病毒的猴子，甚至在感染的晚期，ZMapp也能发挥作用，先前有7个人感染埃博拉病毒只有以ZMapp治疗，其中2人死亡，科学家说，效果令人鼓舞。
ZMapp是利用烟草细胞生产的三种鼠源单克隆抗体的混合药物，对埃博拉病毒外糖标记的蛋白提供人工免疫应答。ZMapp采用烟草作为生物反应器，通过瞬时表达方式在烟草叶片生产单克隆抗体蛋白，经感染后大约一周，收获叶片来生产治疗埃博拉病毒的药物。美国陆军传染病医疗研究所(USAMRIID)、该新药制造商Mapp和KBP等在2012年通过实验表明本氏烟草产生的这三种抗体作为人用药物时优于来自中国仓鼠卵巢细胞(CHO)产出的，并在美国科学院院报PNAS上发表了相关文章。
埃博拉疫情的严重性使人们对ZMapp寄托无限的期望，希望新药能早日征服这种可怕的病毒。
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