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Anti-UNC80 antibody

  • 价  格: ¥4.0 - 4.0
  • 货  号: ab126312
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品牌: abcam
规格: 100 µl
规格: 产品价格: ¥4,773.00
规格: 100 µl 产品价格: ¥4,773.00

Datasheet PDF


Overview
Product name

Anti-UNC80 antibody


Description

Rabbit polyclonal to UNC80


Tested applications

IHC-Pmore details


Cross reactivity

Reacts with


Human


Immunogen

antigen sequence: KDSLNNVVDF LHALLGFCME PVTDNKAGFG NNFTTVDNKS TAQNVEGIIV SAMFKSLITR CASTTHELHS PENLGLYCDI RQLVQFIKEA HGNVFR, corresponding to amino acids of Human UNC80.

KDSLNNVVDFLHALLGFCMEPVTDNKAGFGNNFTTVDNKS TAQNVEGIIVSAMFKSLITRCASTTHELHSPENLGLYCDI RQLVQFIKEAHGNVFR


Positive control

Human hippocampus tissue.


Properties
Form

Liquid


Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.


Storage buffer

pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 59% PBS, 40% Glycerol


Concentration

Concentration information loading...


Purity

Immunogen affinity purified


Clonality

Polyclonal


Isotype

IgG


Research areas

Neuroscience>> Neurotransmission >> Receptors / Channels >> More Ion Channels
Neuroscience >> Neurotransmission >> Receptors / Channels >> Sodium Channels
Neuroscience >> Neurotransmitter >> Neuropeptides >> Tachykinins


Applications
Show applications key

Our Abpromise guarantee covers the use of ab126312 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    IHC-P

      IHC-P: 1/50 - 1/200. Per...Read more →

    IHC-P: 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target
Function

Component of the NALCN sodium channel complex, a cation channel activated either by neuropeptides substance P or neurotensin that controls neuronal excitability.


Sequence similarities

Belongs to the unc-80 family.


Post-translational modifications

Phosphorylated on tyrosine residues.


Cellular localization

Membrane.


Target information above from: UniProt accessionQ8N2C7 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
Alternative names
  • C2orf21 antibody
  • Protein unc-80 homolog antibody
  • UNC 80 antibody
  • Unc 80 homolog (C. elegans) antibody
  • Unc80 antibody
  • UNC80_HUMAN antibody
see all

Database links
Anti-UNC80 antibody images:

  Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-UNC80 antibody (ab126312)

ab126312 at 1/50 dilution staining UNC80 in Paraffin-embedded Human hippocampus tissue by Immunohistochemistry.

References for Anti-UNC80 antibody (ab126312)

ab126312 has not yet been referenced specifically in any publications.

Publishing research using ab126312 ? Please let us know so that we can cite the reference in this datasheet

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trwellplateunderoptimizedconditions(finalconc.10nM)ReferenceDataRefSeq:NM_032504NM_182587XM_117370Synonyms:C2orf21;UNCxzyxtr80...
backgroundRabbitPolyclonalantibodytoUNC80Formalin-fixedandparaffinembeddedratbrainlabeledwithAnti-UNC80PolyclonalAntibody...
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