Dendritic Poly (Glu, Lys)1:2 (Free polybase, 20-40k) Powerful and versatile DNA and siRNA transfection reagent Core dendritic poly(glu,Lys)1:1
Surface Lys
1) forming neutral complex that invests stability in vitro and in vivo transfection
2) forming weak DNA complex that make dissociate easily to express the gene
3) transferring the gene from endosomal compartment to cytosol